Microbiology Courses

  

Course schedules change on a regular basis. Please check ozone.ou.edu for course listings for a given semester. Courses are listed as offered in the Fall (F), Spring (Sp), and Summer (Su) sessions.  Some courses are offered intermittently.
 

HON 3513-900 INTRODUCTION TO BIOTECHNOLOGY
 Prerequisite: BIOL/PBIO 1114 or BIOL 1134
 Biotechnology is often dismissed as biology-for-profit. In reality, it is the application of biological organisms, systems or processes to the manufacturing and service sectors. In this course, I focus on those areas that are receiving the most attention today. I also emphasize the impact or potential impact that biotechnology is having on quality of life. The topics covered are of general interest to majors in chemistry, zoology, microbiology, botany, and pre-meds. Chemical engineering students with strong biomedical interests have taken this course in the past. The areas covered include: (A) recombinant DNA technology principles and applications including protein engineering; (B) various medical biotechnology applications such as monoclonal antibody technology, viral vaccines, gene therapy, genetic testing, gene silencing, stem cell therapies, etc. (C) aquatic biotechnology; (D) forensic biotechnology applications; (E) microbial pathways for bioremediation and alternative energy sources including pathway engineering.(F) Instructor: Karr

MBIO 2815 INTRODUCTION TO MICROBIOLOGY
 Prerequisite: one course in college chemistry. Introduction to microorganisms as biological entities. Survey of the roles of microorganisms in the ecosystem. Application of microorganisms to industrial and environmental problems. Discussion of microorganisms as causes of human disease and response of hosts to microbial invasion. This course does not count for major credit in microbiology or botany (F,Sp,Su) Instructor: Meysick

MBIO 3113 CELL BIOLOGY (Crosslisted with Plant Biology and Biology 3113)
 Prerequisite: PBIO 1114 or BIOL 1134 or BIOL 1114 and BIOL 1121 or BIOL 1124 and Chemistry 3053. Introduction to the cell as a unit of life. A chemical and physical comparison of procaryotic and eucaryotic cells to include a discussion of cell metabolism, types of metabolic regulation, and an analysis of ultrastructure. Emphasis will be placed on the dynamic changes in metabolism and ultrastructure which occur during the life of a cell. (F,Sp, Su[intermittent]), Instructor: BIOL TBD (F)/Wawrik (Sp)

Catalog Entries MBIO 3673 PRACTICAL BIOINFORMATICS(Crosslisted with PBIO 3673) Prerequisite: MBIO 2815, or MBIO 3813, or PBIO 1114, or BIOL 1005, or BIOL 1114, or equivalent introductory biology course, and junior standing, or instructor permission. Study of the use of computers to analyze and interpret various types of biological data. Topics covered will include accessing genomics databases, aligning DNA and protein sequences, searching genomic databases for similar sequences, analyzing protein structure, and building molecular phylogenies. Classes will emphasize group work and in-class computer exercises in a highly interactive environment. (Sp)

MBIO 3812 FUNDAMENTALS OF MICROBIOLOGY LABORATORY
 Prerequisite: Credit or concurrent enrollment in MBIO 3813. Fundamental microbiological methods: aseptic technique, culture methods, microscopy, metabolic and physiological tests, bacterial isolation and identification, environmental microbiology. (F,Sp,Su) Laboratory, Instructor: Meysick
 

MBIO 3813 FUNDAMENTALS OF MICROBIOLOGY
 Prerequisite: One course in college biology and Chemistry 3053 (Organic Chemistry). Cell structure of Procaryotes and microbial Eucaryotes; survey of major groups of Eucaryotic and Procaryotic protists; metabolic characteristics and ecological roles; growth; symbiotic relationships; genetics. (F,Sp), Instructor: Nagle

MBIO 4723 BIOCATALYSIS AND BIOREMEDIATION (Slashlisted with MBIO 5723)

Prerequisites: MBIO 3813 and one semester of Organic Chemistry (CHEM 3053) or Biochemistry (CHEM 3653), or permission of instructor. Introduces the role of microorganisms in the biocatalysis and bioremediation of relevant pollutants. Focuses on bioremediation strategies, the physiology of aerobes vs. anaerobes, biocatalysis and genetics of biodegradation pathways, and methods for monitoring in situ biodegradation. No student may earn credit for both 4723 and 5723. (Sp), Instructor: Callaghan 

MBIO 4810 ADVANCED MOLECULAR BIOLOGY (Slashlisted with MBIO 5810)
 Prerequisite: Intro. Biochemistry or MBIO 4843 or permission of instructor. In this course, students will move beyond their introductory textbooks towards a deeper understanding of modern molecular biology. This will be accomplished by a combination of lectures, readings in the primary literature, and independent scholarly exercises (e.g., development of concept maps and writing assignments). Lectures and readings will focus on comparisons of “traditional” and cutting-edge molecular techniques as they are currently applied towards solving important biological questions. Special emphasis will be placed on the advantages and disadvantages of specific molecular techniques. (Sp), Instructor: Holt/Dunn/Bartley

MBIO 4810 BIOTECHNOLOGY TO ADDRESS SOCIETAL CHALLENGES
 Prerequisites: PBIO/BIOL3113 or PBIO/BIOL3333 or PBIO/MBIO/BIOL 4843 or PBIO/MBIO4873 or CHEM3653 or permission from an instructor.
 Biotechnology is the multidisciplinary approach of applying organisms and biological molecules to specific uses. For the past 30 years and at an ever-increasing pace, public and private sector scientists have used biotechnology to help meet social needs.  Intended for students from diverse academic programs who possess a working knowledge of molecular biology, this course will cover important past achievements and future goals for use of biotechnology to address pressing societal challenges. Participants will put into practice central methods of biotechnology in the laboratory portion, gaining practical skills for use in future careers in laboratory science. (Intermittent), Instructor: Bartley/Libault

MBIO 4883 WATER MICROBIOLOGY
 Prerequisites: MBIO3813 or permission from an instructor.
 Water is becoming one of our most precious resources. The increasing demand for water due to population growth and industrialization is making water availability a critical issue for many societies. Poor water quality is a major cause of disease and death worldwide. We will study the causes and prevention of waterborne microbial diseases and the use of microorganisms to improve water quality. Real-life examples will be used to illustrate the problems caused by poor water quality and solutions to these problems. Topics that will be covered include: waterborne diseases, methods to detect waterborne pathogens, epidemiology, indicator organisms, water quality standards, treatment of drinking water and sewage, and groundwater contamination. (Intermittent), Instructor: McInerney

MBIO 4810 CORNERSTONE IN MICROBIOLOGY
 Prerequisite: permission of instructor.
 Contact instructor for more information.
 (Intermittent), Instructor: Tanner

MBIO 4810 MARINE MICROBIOLOGY (Slashlisted with MBIO 5810)
 Prerequisite: Permission of instructor. A basic introduction into concepts of oceanography and how they relate to microbial processes in marine systems. Topics include: ocean circulation, biogeochemical cycling, microbial ecology, phytoplankton ecology, productivity.
 (Intermittent), Instructor: Wawrik

MBIO 4810 TOPICS IN VIROLOGY (Slashlisted with MBIO 5810)
 Prerequisite: permission of instructor.
 Contact instructor for more information.
 (Intermittent), Instructor: Karen Meysick

MBIO 4813 ECOLOGY AND PATHOGENIC MICROBIOLOGY LABORATORY
 Prerequisite: MBIO 3812 and 3813 or equivalent. Course incorporates laboratory approaches and techniques for the study, characterization and manipulation of individual microorganisms and microbial communities involved in pathogenesis and environmental processes. Contemporary molecular techniques including PCR, recombinant DNA, DNA/RNA analysis, immunological analysis will encompass a large part of this laboratory course. Students will also become acquainted with approaches to discover the mechanisms microorganisms use to establish their ecological niche in both pathogenic and environmental settings. (Sp), Instructor: Krumholz

MBIO 4823/G4823 PATHOGENIC MICROBIOLOGY AND INFECTIOUS DISEASE
 Prerequisite: Microbiology 3812 and 3813. Introduces the basic methods for pathogenic microbiology and infectious disease epidemiology. Topics covered include definitions and nomenclature, outbreak investigations, disease surveillance, case-studies, laboratory diagnosis, immunology, molecular epidemiology, dynamics of transmission, and vaccine effectiveness. Emerging pathogens, their effects on society and the health care services will also be addressed. (F), Instructor: Lawson

MBIO 4833/G4833 BASIC IMMUNOLOGY 
 Prerequisite: one semester of organic chemistry, and an introductory biology course, plus one of the following: 3812, 3813, Biology 2124, 3113, 3204, 3333 or biochemistry or graduate standing and permission. Fundamentals of immunochemistry, cellular immunology, immunogenetics, and clinical immunology. (Sp), Instructor: Collamore

MBIO 4843 INTRODUCTION TO MOLECULAR BIOLOGY
 (Crosslisted with PBIO, BIOL 4843; Slashlisted with 5843.)
 Prerequisites: MBIO 3812 and 3813 or PBIO 1114 or BIOL 1114 or BIOL 1124 or BIOL 1134 and one course in organic chemistry. Introduction to the characteristics and biological functions of nucleic acids and proteins in living cells with emphasis on nucleic acid replication, transcription, translation and regulation; also emphasis on the molecular aspects of microbial genetics-transformation, transduction and conjugation; and emphasis on molecular immunology and genetic engineering/recombinant DNA technology. No student may earn credit for both 4843 and 5843). (F,Sp), Instructor: Dunn (F)/Karr (Sp)

MBIO 4853/4853G PHYSIOLOGY OF MICROORGANISMS
 Prerequisite: MBI0 3812, 3813 and a course in organic chemistry. Diversity, metabolism, energetics and physiology of microorganisms. (Sp), Instructor: McInerney

MBIO 4864 GEOMICROBIOLOGY (Slashlisted with MBIO 5864. Crosslisted with Geology 4864)
 Prerequisite: MBIO 3813 or permission of instructor. Life below the earth's surface. Bacterial degradation of pollutants. Petroleum microbiology. Role of microorganisms in geochemical cycling of carbon, sulfur and metals. No student may earn credit for both 4864 and 5864. (F), Instructor: Krumholz
 

MBIO 4873 MICROBIAL PHYSIOLOGY & MOLECULAR BIOLOGY LABORATORY 
 (Crosslisted with PBIO 4873)
 Prerequisite: Eight hours of biology and permission of instructor. Current techniques to explore molecular aspects of gene expression and regulation. Experiments include: plasmid and phage propagation. Nucleic acid purification, DNA and protein manipulation, and gene analysis. (F). Instructor: Wawrik/Stevenson
 

MBIO 4893 CAPSTONE IN MICROBIOLOGY
 Prerequisite: 3 hrs Calculus, MBIO 3812, 3813, coreq. or prereq. MBIO 4843. Combines laboratory research experiences, primarily in the areas of microbial diversity, physiology, and genetics, with an introduction to how research in microbiology is carried out. (F,Sp), Instructor: Tanner(F)/Savage-Ashlock (Sp)

MBIO 4950 SENIOR THESIS-CAPSTONE
 1 to 6 hours. Prerequisite: MBIO 3813 and permission of instructor. May be repeated for credit; maximum credit six hours. A minimum total of six hours is required. This is a capstone course allowing students to carry out individual research projects under a faculty mentor. Students will present research results orally, in a poster session, and by writing a senior thesis. Honors research credit may substitute for some or all senior thesis credits. (F,Sp,Su), Instructor: Suflita

MBIO 4953 BIOWRITING

(Slashlisted with 5953; Crosslisted with BIOL/PBIO 4953) Prerequisite: permission of instructor. This course provides students engaged in research with the information and skills needed to effectively communicate as professional biologists. Students will learn to report the results of their own research in the format of a journal article, conference-style presentation, and poster. No student may earn credit for both 4953 and 5953. (Irreg.), Instructor: Hoefnagels

MBIO G5364 TRANSMISSION ELECTRON MICROSCOPY (Crosslisted with PBIO and BIOL)
 Prerequisite: Permission of instructor. Introduction to the theory of transmission electron microscopy and practical instruction in specimen preparation, ultramicrotomy, instrument operation, photography, and quantitative methods. (F), Instructor: Russell
 

MBIO G5374 SCANNING ELECTRON MICROSCOPY (Crosslisted with PBIO and BIOL 5374)
 Prerequisite: basic chemistry; basic physics; demonstrated need; permission of instructor. Principles of Scanning Electron Microscopy combined with training in the operation of the SEM and ancillary equipment. Students will be certified in the operation of all equipment. Sample preparation on a variety of samples and darkroom procedures will be performed. Independent project with oral report and poster required. (Sp), Instructor: Larson

MBIO G5453 ADVANCED ECOLOGY AND EVOLUTIONARY BIOLOGY
 (Crosslisted with PBIO & BIOL)
 Prerequisite: general ecology. Required for students in the ecology and evolutionary biology doctoral program. An introduction to current research opportunities and research programs in ecology and evolutionary biology at the University of Oklahoma. Specific topics and lecturers will vary from week to week to give students a broad overview of ongoing research projects. (F) Instructor: Kaspari

MBIO 5471 SEMINAR IN ECOLOGY AND EVOLUTIONAL BIOLOGY (Crosslisted with PBIO and BIOL)
 Prerequisite: graduate standing. Two semesters of enrollment are required for students in the ecology and evolutionary biology doctoral program. An intensive, student-based seminar in which students present both proposals and ongoing progress reports on doctoral level research projects in ecology and evolutionary biology (F,Sp) Instructor: Weider

MBIO 5723 BIOCATALYSIS AND BIOREMEDIATION (Slashlisted with MBIO 4723)

Prerequisites: MBIO 3813 and one semester of Organic Chemistry (CHEM 3053) or Biochemistry (CHEM 3653), or permission of instructor. Introduces the role of microorganisms in the biocatalysis and bioremediation of relevant pollutants. Focuses on bioremediation strategies, the physiology of aerobes vs. anaerobes, biocatalysis and genetics of biodegradation pathways, and methods for monitoring in situ biodegradation. No student may earn credit for both 4723 and 5723. (Sp), Instructor: Callaghan

MBIO 5883 ADVANCED MOLECULAR BIOLOGY (Slashlisted with MBIO 4810)
 Prerequisite: Intro. Biochemistry or MBIO 4843 or permission of instructor. In this course, students will move beyond their introductory textbooks towards a deeper understanding of modern molecular biology. This will be accomplished by a combination of lectures, readings in the primary literature, and independent scholarly exercises (e.g., development of concept maps and writing assignments). Lectures and readings will focus on comparisons of “traditional” and cutting-edge molecular techniques as they are currently applied towards solving important biological questions. Special emphasis will be placed on the advantages and disadvantages of specific molecular techniques. (Sp) Instructor: Holt/Dunn

MBIO 5810 ADVANCED TOPICS ON MICROBIAL ENVIRONMENTAL GENOMICS
 Prerequisite: graduate standing.
 Contact instructor for more information. (Intermittent), Instructor: Jizhong Zhou

MBIO 5810 MARINE MICROBIOLOGY (Slashlisted with MBIO 4810)
 Prerequisite: Permission of instructor. A basic introduction into concepts of oceanography and how they relate to microbial processes in marine systems. Topics include: ocean circulation, biogeochemical cycling, microbial ecology, phytoplankton ecology, productivity. (Intermittent), Instructor: Wawrik
 

MBIO 5810 FUNCTIONAL GENOMICS
 Prerequisite: Permission of instructor. (Intermittent)
 Contact instructor for more information. Instructor: TBD
 

MBIO 5810 METAGENOMICS IN MICROBIAL ECOLOGY: THEORY AND PRACTICE
 Prerequisite: Permission of instructor.
 Development of metagenomic approaches and advances in next generation sequencing have opened new dimensions in microbial ecology research. This course will focus on the power and limitations of metagenomics, as well as important issues regarding experimental design. The course will include a significant amount of “hands-on” instruction in bioinformatics. We will 1) conduct multiple sequence alignments and the build phylogenetic trees using MEGA and the software package ARB, 2) analyze datasets of PCR-amplified gene sequences for microbial community ecology using the mothur and QIIME software packages, and 3) analyze metagenomes using the datasets and tools available on the analysis servers IMG/M and MG-RAST. The goals for this course are to 1) introduce metagenomics to graduate level students, 2) explore strategies for incorporating these approaches in a research program, and 3) gain firsthand experience in processing, analyzing, and visualizing metagenomic data. We will be taking advantage of upgraded macbook pro laptop computers available from the department (personal computers may also be used) and access to online servers at OU and around the globe. (Intermittent), Instructor: Stevenson

MBIO G5833 INDUSTRIAL AND APPLIED MICROBIOLOGY
 Prerequisite: 4843 and 4853 and one semester of calculus. The application of fundamental principles of microbiology to industrial fermentations and processing, food manufacture and preservation and environmental quality and sanitation. (Intermittent), Instructor: McInerney

MBIO G5843 INTRODUCTION TO MOLECULAR BIOL. (Crosslisted with PBIO, BIOL. 5843; Slashlisted with 4843)
 Prerequisite: 3812 and 3813 or PBIOL 1114 or BIOL 1114 or BIOL 1124 or BIOL 1134 and one course in organic chemistry. Introduction to the characteristics and biological functions of nucleic acids and proteins in living cells with emphasis on nucleic acid replication, transcription, translation and regulation; also emphasis on the molecular aspects of microbial genetics-transformation, transduction and conjugation; and emphasis on molecular immunology and genetic engineering/recombinant DNA technology. No student may earn credit for both 4843 and 5843. (F,Sp) Instructor: Dunn (F)/Karr(Sp)

MBIO 5864 GEOMICROBIOLOGY (Slashlisted with MBIO 4864. Crosslisted with Geology 5864)
 Prerequisite: MBIO 3813 or permission of instructor. Life below the earth's surface. Bacterial degradation of pollutants. Petroleum microbiology. Role of microorganisms in geochemical cycling of carbon, sulfur and metals. No student may earn credit for both 4864 and 5864. (F), Instructor: Krumholz

MBIO 5953 BIOWRITING
 (Slashlisted with 4953; Crosslisted with BIOL/PBIO 4953) Prerequisite: permission of instructor. This course provides students engaged in research with the information and skills needed to effectively communicate as professional biologists. Students will learn to report the results of their own research in the format of a journal article, conference-style presentation, and poster. No student may earn credit for both 4953 and 5953. (Irreg.), Instructor: Hoefnagels

MBIO G5971 SEMINAR IN MICROBIOLOGY
 Prerequisite: permission. Required of all graduate students in microbiology. May be repeated; maximum credit two hours for the master's degree, six hours for the doctor’s degree. No laboratory. Topics are selected from various areas of microbiology, and each student is called upon for discussion or formal presentations. (F,Sp), Instructor: Suflita

MBIO 6003 ECOLOGICAL MODELING (Crosslisted with Botany and Zoology)
 Prerequisite: One course in Computer Science, one course in Ecology, or permission of instructor. Trains students to use modeling tools in their research and to gain greater ability to understand, appreciate,and criticize modeling work. Students will learn general procedure and principles with case studies of successful models in ecology and participate in course projects to gain hands-on experience in model development. (F even-numbered years), Instructor: Luo

MBIO G6813 ADVANCED BACTERIAL METABOLISM
 Prerequisite: 3812, 3813 plus six hours of microbiology, biochemistry, organic chemistry or permission. Recent advances in bacterial metabolism will be covered with emphasis on unusual bacterial pathways and on the biotransformations of environmentally significant materials. (F even-numbered years), Instructor: Suflita

MBIO G6853 RECENT ADVANCES IN MICROBIAL PHYSIOLOGY
 Prerequisite: 4843, 4853 and a class in biochemistry. Recent advances in microbial physiology will be covered with emphasis on current literature. (Sp even numbered years), Instructor: Nagle

MBIO G6873 MICROBIAL ECOLOGY
 Prerequisite: 3812, 3813 plus two courses in microbiology or 3812, 3813 plus one microbiology course and one ecology course; biochemistry; calculus; or permission. Advanced treatment of the development and interactions of microbial communities with their living and abiotic environment. Emphasis placed on experimental approaches and on the quantitative concepts of the subject matter. Topics include a kinetic evaluation of microbial activities, global carbon cycling, biodegradation of environmentally significant materials and techniques used in the study of microbial ecology. (F odd-numbered years), Instructor: Suflita

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