Room 32 George Lynn Cross Hall
770 Van Vleet Oval
Norman, OK 73019
BSc, Paris 7 Denis Diderot University, France, 1999
Master Sc, Paris 6 Pierre et Marie Curie University, France, 2000
Ph.D., Paris Sud-Orsay University, France, 2004
Postdoc, University of Missouri, 2005-2011
Research Areas: Plant Biology, Molecular and Cellular biology, Environmental Science
Libault Lab Website
The purpose of my work is to study an innovative plant cell model, the soybean root hair cell, to investigate the transcriptional and epigenetic regulation of gene expression in response to environmental stresses. The integration of the epigenome and transcriptome at the level of a single cell model will also definitively increase our understanding of the impact of epigenetic regulation of gene expression.
The unique properties and functions of the soybean root hair cell (e.g. water and nutrient uptake, infection by symbiotic nitrogen-fixing bacteria) makes this single cell type an attractive model to understand the genetic and epigenetic changes occurring in a plant cell in response to diverse stresses (e.g. drought, pH stresses, nutrient deprivation, etc.). My goal is to utilize this system to understand the role of various genetic and epigenetic regulatory circuits (i.e., transcriptome, transcription factor protein-protein and protein-DNA interactions, DNA methylome, histone acetylome and methylome, small RNA population) in modulating the development and physiology of a single plant cell type. Ultimately, my research will improve plant adaptation to environmental stresses to sustainably enhance crop production.
Kim KD, El Baidouri M, Abernathy B, Iwata-Otsubo A, Chavarro C, Gonzales M, Libault M, Grimwood J and Jackson SA (2015). A Comparative Epigenomic Analysis of Polyploidy-Derived Genes in Soybean and Common Bean. Plant Physiol. 2015 Aug;168(4):1433-47
Qiao Z and Libault M (2013) Unleashing the potential of the root hair cell as a single plant cell type model in root systems biology. Frontiers in Plant Systems Biology. 4:484.
Libault M, Brechenmacher L, Cheng J, Xu D and Stacey G. (2010) Root hair systems biology. Trends in Plant Science. 11: 641-50.
Libault M, Farmer A, Joshi T, Takahashi K, Langley RJ, Levi FD, He J, Xu D, May GD and Stacey G. (2010) An integrated transcriptome atlas of the crop model Glycine max and its use in comparative analyses in plants. The Plant Journal. 63(1):86-99.
Libault M, Zhang XC, Govindarajulu M, Ong YT, Brechenmacher L, Berg H, Hurley-Sommer A, Qiu J, Taylor CG and Stacey G. (2010) A member of the highly conserved FWL (tomato FW2.2-like) gene family is essential for soybean nodule organogenesis. The Plant Journal. 62(5):852-64.
Libault M, Farmer A, Brechenmacher L, Drnevich J, Langley RJ, Bilgin DD, Radman O, Neece DJ, Clough SJ, May GD and Stacey G. (2010) Complete transcriptome of soybean root hair cell, a single cell model, and its alteration in response to Bradyrhizobium japonicum infection. Plant Physiol. 152(2):541-52. Plant Systems Biology Special Issue 2010.