138 George Lynn Cross Hall
770 Van Vleet Oval
Norman, OK 73019
BSc, Biology, University of Windsor 1987
MSc, Microbiology, University of Ottawa 1990
PhD, Microbiology, University of Ottawa 1996
Postdoc, Uniformed Services University 1996-2000
Research areas: Microbiology (specifically pathogenic microbiology)
My scientific training is in bacterial pathogenesis and understanding how bacterial virulence factors contribute to disease. Specifically my research interests focus on bacterial toxins and their mode of action (i.e., how they work). Having previously worked at the Food and Drug Administration (FDA) in the field of bacterial vaccines another research interest of mine is in the development of vaccines against various infectious agents.
Madore, D.V., B.D. Meade, F. Rubin, C. Deal, F. Lynn and Meeting Contributors. 2010. Utilization of serological assays to support efficacy of vaccines in nonclinical and clinical trials: meeting at the crossroads. Vaccine 28(29):4539-4547.
Meysick, K. C., J. Seidman, and J. R. Falconio. 2009. The Yersinia pseudotuberculosis YplA phospholipase differs in its activity, regulation and secretion from that of the Yersinia enterocolitica YplA. Microbial Pathogenesis 47(1):24-32.
Grande, K. K., K. C. Meysick, S. B. Rasmussen and A. D. O’Brien. 2009. Cytotoxic necrotizing factor type 1 (CNF1)- neutralizing monoclonal antibody NG8 recognizes three amino acids in a C-terminal region of the toxin and reduces toxin binding to Hep-2 cells. Infection and Immunity 77(1):170-179.
McNichol, B. A., S. B. Rasmussen, K. C. Meysick and A.D. O’Brien. 2006. A single amino acid substitution in the enzymatic domain of cytotoxic necrotizing factor type 1 of Escherichia coli alters the tissue culture phenotype to that of the dermonecrotic toxin of Bordetella spp.. Molecular Microbiology 60(4):939-950.
Meysick, K. C., M. Mills and A. D. O’Brien. 2001. Epitope mapping of monoclonal antibodies capable of neutralizing cytotoxic necrotizing factor type 1 of uropathogenic Escherichia coli. Infection and Immunity 69(4):2066-2074.